反应详情

温度

45 °C

A mixture containing 147 mmol of D-tryptophan, 294 ml of 1 N sulfuric acid, 300 ml of ethanol and 294 mmol of octanal is stirred at 45° C. for 72 hours. The solution is concentrated and the residue is taken up in a water/methanol/ammonium hydroxide mixture. The methanol is evaporated at 45° C. and the precipitate is filtered off, washed with water and dried. The solid obtained is solubilized at high temperature in methanol. After cooling, the compound of preparation F crystallizes. It is then filtered and dried.

1. concentrationThe solution is concentrated
2. customThe methanol is evaporated at 45° C.
3. filtrationthe precipitate is filtered off
4. washwashed with water
5. customdried
6. customThe solid obtained
7. temperatureAfter cooling
8. customthe compound of preparation F
9. customcrystallizes
10. filtrationIt is then filtered
11. customdried