Pyridine → HCID 54535103, compound

Participants

Reaction Steps

A solution of 0.3 g (1.37 mmol) of methyl 2-hydroxy-4,7-dimethylindole-2-carboxylate and 0.13 ml of pyridine in 20 ml of anhydrous THF was cooled, to 0° C. and 0.12 ml of acetyl chloride was gradually added dropwise. The reaction mixture was stirred for 1 hour and then added dropwise to ice water. The crystals were separated by filtration and dried under reduced pressure to provide 0.30 g of green crystals. Yield: 92%

Provenance & Evidence