Tetraethyl vinylidene phosphonate → [4-Oxo-pentylidene]bisphosphonic acid tetraethyl ester

HRID 36166Notes

Reaction equation

HRID 36166 reaction equation
[CH2:1]([O:3][P:4]([C:9]([P:11](=[O:18])([O:15][CH2:16][CH3:17])[O:12][CH2:13][CH3:14])=[CH2:10])(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2].C[O:20][C:21]1[CH:41]=CC2N=C(NC(=O)CC(=O)C3C=CC=CC=3)SC=2[CH:22]=1>>[CH2:16]([O:15][P:11]([CH:9]([P:4](=[O:8])([O:5][CH2:6][CH3:7])[O:3][CH2:1][CH3:2])[CH2:10][CH2:22][C:21](=[O:20])[CH3:41])(=[O:18])[O:12][CH2:13][CH3:14])[CH3:17]

Participants

3

Reactant 2

HCID 11022954Tetraethyl vinylidene phosphonateHCID 19975336N-(6-methoxybenzothiazol-2-yl)-3-oxo-3-phenylpropanamide

Product 1

HCID 53915615[4-Oxo-pentylidene]bisphosphonic acid tetraethyl ester

Procedure

Ethenylidenebisphosphonic acid tetraethyl ester (I) and acetone (II), MS (m/e) 358, 316, 301, 288, 261, 233, 221, 179 and 152; CMR (CDCl3) 207.5, 62.4, 41.4, 34.8, 19.4 and 16 δ.

Sources & evidence

ORD record
ord-a0d161b10a4e46909b898607657b28fc
Source dataset
uspto-grants-1995_05
Patent number
US05412141

Reaction notes

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