Acetic Acid → HCID 86753647, compound

HRID 361674Notes

Reaction equation

[N+:1]([O-:4])([O-:3])=[O:2].[NH4+].[Ce].[C:7]([O:10][C:11]1[CH:28]=[CH:27][C:26]2[C@@H:25]3[C@H:16]([C@H:17]4[C@@:21]([CH2:23][CH2:24]3)([CH3:22])[C@@H:20]([O:29][C:30](=[O:32])[CH3:31])[CH2:19][CH2:18]4)[C@H:15]([CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][S:42]([CH2:45][CH2:46][CH2:47][C:48]([F:54])([F:53])[C:49]([F:52])([F:51])[F:50])(=[O:44])=[O:43])[CH2:14][C:13]=2[CH:12]=1)(=[O:9])[CH3:8].C(O)(=[O:57])C>>[C:7]([O:10][C:11]1[CH:28]=[CH:27][C:26]2[C@:25]3([OH:57])[C@H:16]([C@H:17]4[C@@:21]([CH2:23][C@@H:24]3[O:2][N+:1]([O-:4])=[O:3])([CH3:22])[C@@H:20]([O:29][C:30](=[O:32])[CH3:31])[CH2:19][CH2:18]4)[C@@H:15]([CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][S:42]([CH2:45][CH2:46][CH2:47][C:48]([F:54])([F:53])[C:49]([F:50])([F:51])[F:52])(=[O:43])=[O:44])[CH2:14][C:13]=2[CH:12]=1)(=[O:9])[CH3:8]

Participants

Reactant 3

HCID 176Acetic Acid

HCID 57262262HCID 57262262, compound

HCID 57418452Ammonium cerium-nitrate

Product 1

HCID 86753647HCID 86753647, compound

Procedure

18.6 g of cerium ammonium nitrate is added to a solution of 3.0 g of 3,17β-diacetyloxy-7α-(9-[4,4,5,5,5-pentafluoropentanesulfonyl]-nonyl)-estra-1,3,5(10)-triene in 50 ml of aqueous acetic acid (90%), and it is stirred for 4 hours at room temperature.

Sources & evidence

ORD record: ord-65741a472a8547c683348a357bab1031
Source dataset: uspto-grants-1999_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05866560

Reaction notes

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