Potassium Hydroxide → HCID 15542231, compound

HRID 361675Notes

Reaction equation

HRID 361675 reaction equation
C([O:4][C:5]1[CH:22]=[CH:21][C:20]2[C@@H:19]3[C@H:10]([C@H:11]4[C@@:15]([CH2:17][C@@H:18]3[O:23][N+:24]([O-:26])=[O:25])([CH3:16])[C@@H:14]([O:27]C(=O)C)[CH2:13][CH2:12]4)[C@H:9]([CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][S:40]([CH2:43][CH2:44][CH2:45][C:46]([F:52])([F:51])[C:47]([F:50])([F:49])[F:48])(=[O:42])=[O:41])[CH2:8][C:7]=2[CH:6]=1)(=O)C.[OH-].[K+]>CO>[N+:24]([O:23][C@H:18]1[CH2:17][C@@:15]2([CH3:16])[C@@H:11]([CH2:12][CH2:13][C@@H:14]2[OH:27])[C@H:10]2[C@H:19]1[C:20]1[CH:21]=[CH:22][C:5]([OH:4])=[CH:6][C:7]=1[CH2:8][C@H:9]2[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][S:40]([CH2:43][CH2:44][CH2:45][C:46]([F:52])([F:51])[C:47]([F:48])([F:49])[F:50])(=[O:41])=[O:42])([O-:26])=[O:25]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 86753648HCID 86753648, compound

Product 1

HCID 15542231HCID 15542231, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

For saponification, 1.0 g of 3,17β-diacetyloxy-11β-nitrooxy-7α-(9-[4,4,5,5,5-pentafluoropentane-sulfonyl]-nonyl)-estra-1,3,5(10)-triene is dissolved in 50 ml of methanol, mixed with 20 ml of 3% methanolic potassium hydroxide solution and allowed to stand for 4 hours at room temperature.

Sources & evidence

ORD record
ord-dc261d98357e40a6b58e6e14a65edb45
Source dataset
uspto-grants-1999_02
Patent number
US05866560

Reaction notes

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