HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrole-2-Carboxylic Acid → HCID 15392050, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrole-2-Carboxylic Acid | HCID 12473 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 1-Benzyl-4-[N-ethyl-N-(3-(2-methyl-1-propenyl)-2-pyridinyl)amino]piperidine | HCID 10665494 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Product | HCID 15392050 | HCID 15392050 | — |
Reaction Steps
Following the general procedure of EXAMPLE 20 and making non-critical variations but starting with 1-benzyl-4-[N-ethyl-N-(3-(2-methyl-1-propenyl)-2-pyridinyl)amino]piperidine (XXII, EXAMPLE 17, 0.67 g, 1.92 mmol), Pearlman's catalyst (0.1 g), CDI (0.31 g, 1.92 mmol) and pyrrole-2-carboxylic acid (0.213 g, 1.92 mmol), the title compound is obtained, HRMS Calcd. for C21H30N4O=354.2419, found=354.2413.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866589 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-24695953d3f94df9b681d0f94397a880 |
| Source note | uspto-grants-1999_02 |