HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-benzyl-N-methylpiperidin-4-amine → 1-Benzyl-4-[N-ethyl-N-(3-(1-methylethoxy)-2-pyridinyl)amino]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-benzyl-N-methylpiperidin-4-amine | HCID 4136128 | — |
| Reactant | 2-Bromo-3-isopropoxypyridine | HCID 10488883 | — |
| Reactant | 2-Bromo-3-ethoxypyridine | HCID 10631926 | — |
| Product | 1-Benzyl-4-[N-ethyl-N-(3-(1-methylethoxy)-2-pyridinyl)amino]piperidine | HCID 53937325 | — |
Reaction Steps
Following the general procedure of EXAMPLE 70, and making non-critical variations but substituting 1-benzyl-4-(ethylamino)piperidine (EXAMPLE 11) for 1-benzyl-4-(methylamino)piperidine and 2-bromo-3-(1-methylethoxy)pyridine (EXAMPLE 76) for 2-bromo-3-ethoxypyridine, the title compound is obtained, NMR (CDCl3) 7.84, 7.32-7.22, 6.99, 6.68, 4.52, 3.82, 3.49, 3.40, 2.94, 2.00, 1.85, 1.73, 1.31 and 1.02δ.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866589 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-06e6f571f65c4975b770bc992de79232 |
| Source note | uspto-grants-1999_02 |