1-Benzyl-4-[N-ethyl-N-(3-(1,1-dimethylethylamino)-2-pyridinyl)amino]piperidine → 4-[N-Ethyl-N-(3-(1,1-dimethylethylamino)-2-pyridinyl)amino]piperidine
Reaction equation
C([N:8]1[CH2:13][CH2:12][CH:11]([N:14]([CH2:26][CH3:27])[C:15]2[C:20]([NH:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[CH:19][CH:18]=[CH:17][N:16]=2)[CH2:10][CH2:9]1)C1C=CC=CC=1.C(N1CCC(N(CC)C2C(NC(C)C)=CC=CN=2)CC1)C1C=CC=CC=1>>[CH2:26]([N:14]([CH:11]1[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]1)[C:15]1[C:20]([NH:21][C:22]([CH3:25])([CH3:23])[CH3:24])=[CH:19][CH:18]=[CH:17][N:16]=1)[CH3:27]Participants
3
Procedure
Following the general procedure of EXAMPLE 206 and making non-critical variations but substituting 1-benzyl-4-[N-ethyl-N-3-(1,1-dimethylethylamino)-2-pyridinyl)amino]piperidine (EXAMPLE 143) for 1-benzyl-4-[N-ethyl-N-(3-(isopropylamino)-2-pyridinyl)amino]piperidine, the title compound is obtained.
Sources & evidence
- ORD record
- ord-5201dad7809a41938d35f9a0a7cc299d
- Source dataset
- uspto-grants-1999_02
- Patent number
- US05866589
Reaction notes
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