HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-4-[N-ethyl-N-(3-nitro-2-pyridinyl)amino]methylpiperidine → HCID 54076407, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-4-[N-ethyl-N-(3-nitro-2-pyridinyl)amino]methylpiperidine | HCID 57307687 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 54076407 | HCID 54076407 | — |
Reaction Steps
1-Benzyl-4-[(N-ethyl-N-(3-nitro-2-pyridinyl)amino)methyl]piperidine (EXAMPLE 262, 4.70 g) is dissolved in 40 ml of THF and 1.7 g of platinum oxide is added and the reaction is placed on a Parr hydrogenator at 10 psi for 1 hr. Then a further 800 mg of platinum oxide is added and the reaction hydrogenated another hour. Then it is filtered through celite and concentrated under reduced pressure to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866589 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-dffffb50f5d1482ea53f7750fd416762 |
| Source note | uspto-grants-1999_02 |