HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-(Chlorophenylmethylene)bis(4-methoxybenzene) → HCID 18705556, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-(Chlorophenylmethylene)bis(4-methoxybenzene) | HCID 96831 | — |
| Reactant | N-[1,2-Dihydro-1-[1-hydroxy-2-(hydroxymethyl)-4-oxo-3-azetidinyl]-2-oxo-4-pyrimidinyl]benzamide | HCID 18705563 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 18705556 | HCID 18705556 | — |
Reaction Steps
1-N-Hydroxy-3-(N-benzoylcytosin-1-yl)-4-hydroxymethyl-2-azetidinone (10 mmole) is dissolved in pyridine (20 ml) and 4,4'-dimethoxytrityl chloride (12 mmole) is added and stirred under argon for 8 hours. The reaction mixture is concentrated under reduced pressure. The crude product is purified by flash chromatorgraphy using silica gel and ethyl acetate/dichloromethane/1% triethylamine as eluants to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866691 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-61df8fb8be844fa28a0bc99e74c548e3 |
| Source note | uspto-grants-1999_02 |