HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 361946Generated: October 31, 2026
4-Chlorobenzoic Acid → 4-Chlorobenzonitrile
https://huagongshe.com/reaction/361946
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chlorobenzoic Acid | HCID 6318 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Product | 4-Chlorobenzonitrile | HCID 12163 | 1,211.4% |
Reaction Steps
The reaction was carried out as described in Example 1. PCBTC (230 g, 1.0 mol), ammonium chloride (56.2 g,1.05 eq), and p-chlorobenzoic acid (11.5 g) were charged to the reactor. The mixture was heated at 215° C. for 9 h. Distillation of the reaction mixture gave PCBN (122.4 g, 89%, melting point: 92°-93° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05866709 |
|---|
| Source dataset | uspto-grants-1999_02 |
|---|
| ORD ID | ord-8ff0d227052e4de28d9cd529fb8ca266 |
|---|
| Source note | uspto-grants-1999_02 |
|---|
