HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 361971Generated: October 25, 2026
Nitric Acid → 2,6-Dichloro-5'-nitro-4'-methoxy-2'-methyl-benzophenone
https://huagongshe.com/reaction/361971
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 2,6-Dichloro-4'-methoxy-2'-methyl-benzophenone | HCID 54505258 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,6-Dichloro-5'-nitro-4'-methoxy-2'-methyl-benzophenone | HCID 54492291 | — |
Reaction Steps
2,6-Dichloro-4'-methoxy-2'-methyl-benzophenone (0.75 g; 2.5 mmol) is added to nitric acid (10 ml; 65%). The mixture is stirred at 80° C. for 1hour. After addition of water the reaction product crystallises and is chromatographically purified (flash column filled with 30 g of silicagel, elution with toluene). White crystals (0.35 g; 41% y); mp. 156°-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05866722 |
|---|
| Source dataset | uspto-grants-1999_02 |
|---|
| ORD ID | ord-7ffdccfbac954e48aa3458fa8a6fa77a |
|---|
| Source note | uspto-grants-1999_02 |
|---|
