Formaldehyde → HCID 23499685, compound

Participants

Reaction Conditions

Reaction Steps

Into a 100 ml four-necked flask were charged 29.96 g of 1,4-bis[1-(4-hydroxy-3-methylphenyl)-1-methylethyl]benzene["Bis-OC-P" manufactured by Honshu Kagaku Co., Ltd.], 4.48 g of sodium hydroxide and 44.8 g of water. While stirring at 50° C., 25.97 g of 37% formaldehyde was added dropwise thereto over 1 hour, and the reaction was conducted for 1 more hour. After completion of the reaction, 11 g of 90% aqueous acetic acid solution was added for neutralization and then the mixture was cooled to 25° C. Thereafter, 100 g of ethyl acetate and20 g of toluene were added thereto and a phase separation was carried out. The separated solution was concentrated and 100 g of hexane was added to the concentrated mass and it was cooled to 25° C. The resulting mixture was filtered, and the filtered product was rinsed with 100 g of hexane and dried a whole day and night at 45° C. under reduced pressure to obtain 28.75 g of 1,4-bis[1-(4-hydroxy-3-hydroxymethyl-5-methylphenyl)-1-methylethyl]benzene

Provenance & Evidence