Acetic Acid → HCID 10929738, compound

Participants

Reaction Conditions

Reaction Steps

Into a 4 liter four-necked flask were charged 49.66 g of 4,4'-methylenebis[2-(2-hydroxy-5-methylbenzyl)-3,6-dimethylphenol], 9.60 gof sodium hydroxide, 167.1 g of water and 16.7 g of tetrahydrofurane. Whilestirring at 40° C., 48.7 g of 37% formaldehyde was added dropwise thereto over one hour, and the reaction was conducted for 5 more hours. After completion of the reaction, 19.2 g of 90% aqueous acetic acid solution was added for neutralization, then cooled to 25° C. and filtered. The filtered product thus obtained was rinsed with 100 g of deionized water and dried a whole day and night at 45° C. under reduced pressure to obtain 48.2 g of 4,4'-methylenebis[2-(2-hydroxy-3-hydroxymethyl-5-methylbenzyl)-3,6-dimethylphenol].

Provenance & Evidence