Acetic Acid → HCID 86753692, compound

Participants

Reaction Conditions

Reaction Steps

Into a four-necked flask were charged 78.7 parts of 4,4'-methylenebis[2-(4-hydroxy-2,5-dimethylbenzyl)-3,6-dimethylphenol], 28.8 parts of sodium hydroxide, 850 parts of water and 150 parts of tetrahydrofurane and they were completely dissolved. While stirring at 40° C., 73.0 parts of 37% formaldehyde was added dropwise thereto and the reaction was conducted for 6 hours. After completion of the reaction, 45.0 parts of acetic acid was added for neutralization and then the mixture was cooled to 25° C. Thereafter, the precipitated crystalline product was filtered out and rinsed with 1000 parts of deionized water. The filtered product was dried a whole day and night under reduced pressure at 45° C. to obtain 71.9 parts of 4,4'-methylenebis[2-(4-hydroxy-3-hydroxymethyl-2,5-dimethylbenzyl)-3,6-dimethylphenol]

Provenance & Evidence