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HRID362051

反应详情

EQUATION

反应方程式

HRID 362051 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N1CCNCC1
HCID143452

tert-Butyl piperazine-1-carboxylate

C9H18N2O2

结构：COc1ccc(CS[C@H]2C[C@@H](C(=O)O)N(C)C2)cc1
HCID15297072

未命名化合物

结构：CC(=N)NC(=O)OCc1ccc([N+](=O)[O-])cc1
HCID140352007

未命名化合物

PRODUCTS

生成物

1
结构：CC(=NC(=O)OCc1ccc([N+](=O)[O-])cc1)N1CCN(C(=O)[C@@H]2C[C@H](S)CN2C)CC1
HCID131720425

未命名化合物

收率 49.9%

PROCEDURE

实验过程

Following a procedure similar to that described in Preparation 1, but using 282 mg of (2S,4S)-4-(4-methoxybenzylthio)-1-methyl-2-pyrrolidinecarboxylic acid, 203 mg of 1-t-butoxycarbonylpiperazine and 258 mg of N-(4-nitrobenzyloxycarbonyl)acetamidine, 225 mg of the title compound were obtained as a viscous oil.

WORKUP

后处理

  1. customthat described in Preparation 1