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HRID362052

反应详情

EQUATION

反应方程式

HRID 362052 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)C(=O)Cl
HCID62493

2,2-Dimethylpropanoyl chloride

C5H9ClO

结构：COc1ccc(CS[C@H]2C[C@@H](C(=O)O)N(C)C2)cc1
HCID15297072

未命名化合物

结构：O=C(N[C@H]1CCNC1)OCc1ccc([N+](=O)[O-])cc1.O=C(O)C(F)(F)F
HCID67586712

未命名化合物

PRODUCTS

生成物

1
结构：CN1C[C@@H](S)C[C@H]1C(=O)N1CC[C@H](NC(=O)OCc2ccc([N+](=O)[O-])cc2)C1
HCID11143993

未命名化合物

收率 71.6%

PROCEDURE

实验过程

Following a procedure similar to that described in Preparation 18, but using 1.03 g of (2S,4S)-4-(4-methoxybenzylthio)-1-methyl-2-pyrrolidinecarboxylic acid, 463 mg of pivaloyl chloride and 1.45 g of (3S)-3-(4-nitrobenzyloxycarbonyl)aminopyrrolidine trifluoroacetate, 1.07 g of the title compound were obtained as a powder.

WORKUP

后处理

  1. customthat described in Preparation 18