Ethanol → HCID 70286678, compound

Participants

Reaction Steps

A mixture of 3-(bromoacetyl)benzo[b]thiophen-5-carbonitrile (1.05 g), 2-imidazolidinethione (0.4 g), ethanol (31.5 ml), and acetic acid (21 ml) was heated under reflux under nitrogen for 24 hours, then cooled in ice. The resulting precipitate was collected by filtration, washed with ether, and dried in vacuo at 65° C. to give 3-(5,6-dihydroimidazo[2,1-b]thiazol-3-yl)benzo[b]thiophen-5-carbonitrile monohydrobromide as a white solid (1 g), m.p. 303°-305° C.

Provenance & Evidence