HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Nitrophenyl)hydrazine → 5-Cyclopropyl-2,4-dihydro-2-(2-nitrophenyl)-3H-1,2,4-triazol-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Nitrophenyl)hydrazine | HCID 3314739 | — |
| Reactant | ethyl N-(carbethoxy)cyclopropanecarboximidate | HCID 54370041 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 5-Cyclopropyl-2,4-dihydro-2-(2-nitrophenyl)-3H-1,2,4-triazol-3-one | HCID 135720084 | 69% |
Reaction Steps
By the procedure of Example 4, Step C, 2-nitrophenylhydrazine was reacted with ethyl N-(carbethoxy)cyclopropanecarboximidate. After work-up, the residue was purified by flash chromatography on silica gel (150 mL for 2.0 mmole, eluted with 1.5% MeOH/CH2Cl2) to give the desired material as a yellow foam in 69% yield, homogeneous by TLC in 5% MeOH/CH2Cl2, mass spectrum (FAB) m/e 247 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05411980 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-bba17d0917914d9fb6f8e3e9787e2847 |
| Source note | uspto-grants-1995_05 |