反应详情

2 g of 5-methyl-2-phenyl-2,4-dihydro-3-pyrazolone, 188 ml of trimethyl orthoformate and 1.29 ml of o-anisidine are heated with stirring in 5 ml of glacial acetic acid at 70° C. for 2 h. The reaction mixture is cooled and 10 ml of methanol are added. The precipitate which has separated out is filtered off with suction and recrystallized from ethyl acetate.

1. temperatureThe reaction mixture is cooled
2. customThe precipitate which has separated out
3. filtrationis filtered off with suction
4. customrecrystallized from ethyl acetate