HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium Fluoride → HCID 22942417, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | HCID 22942424 | HCID 22942424 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22942417 | HCID 22942417 | — |
Reaction Steps
5'-O-(tert-Butyldimethylsilyl)-3'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-(benzoylthio)-uridine (1.4 mmole) was treated with 20 ml of 1.0M tetrabutylammonium fluoride in THF at room temperature for 16 hr. The solvent was removed and the residue was purified on silica gel column chromatography to provide 2'-(benzoylthio)-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05869696 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-7b1db307d9a44dbbab61e94385a4db22 |
| Source note | uspto-grants-1999_02 |