HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-2-(6-fluoro-1-indanylidene)acetamide → (E)-2-(5-fluoro-1-indanylidene)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-2-(6-fluoro-1-indanylidene)acetamide | HCID 9837001 | — |
| Reactant | (E)-2-(6-fluoro-1-indanylidene)acetyl chloride | HCID 15491026 | — |
| Product | (E)-2-(5-fluoro-1-indanylidene)acetamide | HCID 10954366 | 44% |
Reaction Steps
This compound was prepared in a similar manner to that described for (E)-2-(6-fluoro-1-indanylidene)acetamide Example 1k by substituting (E)-2-(5-fluoro-1-indanylidene)acetyl chloride (3.16 g, 0.015 mol) for (E)-2-(6-fluoro-1-indanylidene)acetyl chloride. Recrystallization from acetonitrile: water mixtures gave 1.28 g (44%) of (E)-2-(5-fluoro-1-indanylidene)acetamide as a white solid; m.p., 191°-193° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05872118 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-061ec2a7f1ec41f2874d7ba6bf4b98b2 |
| Source note | uspto-grants-1999_02 |