HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-(2-Fluorophenyl)butyryl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(2-Fluorophenyl)butanoic acid | HCID 15491036 | — |
| Product | 4-(2-Fluorophenyl)butyryl chloride | HCID 15491037 | 100% |
Reaction Steps
A mixture of 4-(2-fluorophenyl)butyric acid (100 g, 0.55 mol) and thionyl chloride (418.8 g, 3.51 mol) was refluxed for 3 h. The excess thionyl chloride was removed in vacuo to give 110.1 g (100%) of 4-(2-fluorophenyl)butyryl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05872118 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-a252478119764ffeabb1fca6dbbaf477 |
| Source note | uspto-grants-1999_02 |