Dichloromethane → HCID 23293574, compound

HRID 362878Notes

Reaction equation

HRID 362878 reaction equation
[F:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]([CH2:15][CH2:16][CH3:17])[CH2:7]/[C:8]/2=[CH:11]\[C:12](O)=[O:13])=[CH:4][CH:3]=1.[Cl:18]CCl>>[F:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]([CH2:15][CH2:16][CH3:17])[CH2:7]/[C:8]/2=[CH:11]\[C:12]([Cl:18])=[O:13])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 23293633HCID 23293633, compound

Product 1

HCID 23293574HCID 23293574, compound

Procedure

This compound was prepared in an analogous manner to Example 18h with replacement of (E)-2-(6-fluoro-3-methyl-1-indanylidnene)acetic acid with (E)-2-(6-fluoro-3-propyl-1-indanylidene)acetic acid (15.01 g, 64.07 mmol). The product residue was dissolved in dichloromethane and used without purification in Example 27j.

Workup

  1. customused without purification in Example 27j

Sources & evidence

ORD record
ord-2124504e721848efac2d2cbcd1618fd0
Source dataset
uspto-grants-1999_02
Patent number
US05872118

Reaction notes

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