Ethanol → 2-(N'-n-Pentylureido)-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide

Participants

Role	Name	HCID	Charge
Reactant	Ethanol	HCID 702	—
Reactant	Pentylamine	HCID 8060	—
Reactant	2-amino-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide	HCID 67594819	—
Product	2-(N'-n-Pentylureido)-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide	HCID 67594899	29.9%

Reaction Steps

{2-amino-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide and n-pentylamine}:yield 29.9%; mp 178°-180° C. (EtOH); 1NMR (DMSO-d6)ppm: 0.86 (3H, t), 1.24-1.83 (13H, m), 2.79 (2H, d), 2.96 (2H, dd), 3.15 (2H, t, ), 4.26 (1H, s), 6.91 (1H, t), 7.13-7.41 (12H, m), 7.57 (1H, d), 8.22 (1H, d), 8.58 (1H, t), 9.93 (1H, s).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05872115
Source dataset	uspto-grants-1999_02
ORD ID	ord-6a5ae23565914335ae1bd75935ee96e2
Source note	uspto-grants-1999_02