HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 2-(N'-n-Hexylureido)-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Hexylamine | HCID 8102 | — |
| Reactant | 2-amino-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide | HCID 67594819 | — |
| Product | 2-(N'-n-Hexylureido)-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide | HCID 67595485 | 56.9% |
Reaction Steps
{2-amino-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide and n-hexylamine}: yield 56.9%; mp 168°-169° C. (EtOH); 1H NMR (DMSO-d6)ppm: 0.86 (3H, t), 125-1.83 (15H, m), 2.79 (2H, d), 3.01 (2H, dd), 3.17 (2H, t), 4.26 (1H, s), 6.91 (1H, t), 7.13-7.40 (12H, m), 7.57 (1H, d), 8.21 (1H, d), 8.57 (1H, t), 9.95 (1H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05872115 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-9a26f685829c493da0cbc0572c98cf27 |
| Source note | uspto-grants-1999_02 |