Butyl isocyanate → 2-(N'-n-Butylureido)-4-chloro-N-[(1-diphenylmethylpiperidin-4-yl)methyl]-benzamide

Participants

Role	Name	HCID	Charge
Reactant	Butyl isocyanate	HCID 8110	—
Reactant	2-amino-4-chloro-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide	HCID 67594690	—
Product	2-(N'-n-Butylureido)-4-chloro-N-[(1-diphenylmethylpiperidin-4-yl)methyl]-benzamide	HCID 67596380	—

Reaction Steps

{2-amino-4-chloro-N-[(1-diphenylmethylpiperidin-4-yl)methyl]benzamide and n-butylisocyanate}: mp 195°-197° C.; 1H NMR (CDCl3)ppm: 0.93 (3H, t), 1.30-1.90 (11H, m), 2.91 (2H, m), 3.24 (2H, td), 3.31 (2H, dd), 4.25 (1H, s), 4.67 (1H, bs), 6.36 (1H, bs), 6.87 (1H, dd), 7.14-7.41 (11H, m), 8.51 (1H, d), 10.38 (1H, s).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05872115
Source dataset	uspto-grants-1999_02
ORD ID	ord-c3c1c8067e1f4ae2befae11bec481c0b
Source note	uspto-grants-1999_02