Aluminium lithium hydride → HCID 54359779, compound

HRID 363028Notes

Reaction equation

HRID 363028 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].[C:7]1([CH2:13][CH:14]([O:22][C:23]2[CH:37]=[CH:36][C:26]([C:27]([NH:29][C:30]3[CH:35]=[CH:34][N:33]=[CH:32][CH:31]=3)=O)=[CH:25][CH:24]=2)[CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[C:16]1([CH2:15][CH:14]([O:22][C:23]2[CH:37]=[CH:36][C:26]([CH2:27][NH:29][C:30]3[CH:35]=[CH:34][N:33]=[CH:32][CH:31]=3)=[CH:25][CH:24]=2)[CH2:13][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 54486187HCID 54486187, compound

Product 1

HCID 54359779HCID 54359779, compound

Procedure

Lithium aluminum hydride reduction of 17-8 (1.36 g, 3.3 mmol) as described in Example 14 gave a quant. yield of the product 17-9 as a viscous oil. The hydrochloride melted at 151°-154° C.

Sources & evidence

ORD record
ord-fff03a14ce0841a5a42fed365a69ec26
Source dataset
uspto-grants-1999_02
Patent number
US05872138

Reaction notes

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