Aluminium lithium hydride → HCID 15838901, compound

HRID 363031Notes

Reaction equation

HRID 363031 reaction equation
[CH2:1]1[O:26][C:25]2[CH:24]=[CH:23][C:5]([CH2:6][O:7][C:8]3[CH:22]=[CH:21][C:11]([C:12]([NH:14][C:15]4[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=4)=O)=[CH:10][CH:9]=3)=[CH:4][C:3]=2[O:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:1]1[O:26][C:25]2[CH:24]=[CH:23][C:5]([CH2:6][O:7][C:8]3[CH:22]=[CH:21][C:11]([CH2:12][NH:14][C:15]4[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=4)=[CH:10][CH:9]=3)=[CH:4][C:3]=2[O:2]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 54518423HCID 54518423, compound

Product 1

HCID 15838901HCID 15838901, compound

Procedure

18-6 (0.32 g, 0.9 mmol) was reduced with lithium aluminum hydride (0.30 g, 8 mmol) as in Example 10. The product 18-7 was obtained as an oil. The hydrochloride salt melted at 190°-193° C.

Sources & evidence

ORD record
ord-915756d8bb8c4e22aa6766e64a9c783b
Source dataset
uspto-grants-1999_02
Patent number
US05872138

Reaction notes

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