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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 363184Generated: October 26, 2026

Water → 6-Phenylnicotinic acid

https://huagongshe.com/reaction/363184

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant5-Methyl-2-phenylpyridineHCID 47467—
ReactantPotassium PermanganateHCID 516875—
Product6-Phenylnicotinic acidHCID 120118—

Reaction Steps

A suspension of 2-phenyl-5-methyl pyridine (1.03 g, 6.09 mmol) and potassium permanganate (2.89 g, 18.3 mmol), in water (25 mL) was heated at reflux for 2 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (1 mL) was added to the colourless filtrate and the product was collected as a white solid by filtration.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05872136
Source datasetuspto-grants-1999_02
ORD IDord-6e644e5ebedd4852bf22e76bd7adb84c
Source noteuspto-grants-1999_02