HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → Azelaic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 8-Cyano-octanoic acid | HCID 11084300 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethyl ether ethylene glycol | HCID 21863332 | — |
| Product | Azelaic Acid | HCID 2266 | — |
Reaction Steps
83.5 g of 8-cyanooctanoic acid dissolved in 300 ml of dimethyl ether ethylene glycol are heated to 130° C. for 4 hours in the presence of 50g of 40% caustic soda. After cooling, the reaction mixture is diluted with water, then acidified to pH 5 with diluted sulfuric acid, and then the precipitated solid is filtered. After drying, 92 g of azelaic acid with a m.p. of 107° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05872267 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-106c0db6ab624e2f871a05c8c526b87c |
| Source note | uspto-grants-1999_02 |