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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 363208Generated: October 30, 2026

Hydrochloric Acid → 3-Amino-N-((phenylmethoxy)carbonyl)-L-alanine methyl ester

https://huagongshe.com/reaction/363208

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethanolHCID 887—
ReactantZ-Dap-OHHCID 2756313—
Product3-Amino-N-((phenylmethoxy)carbonyl)-L-alanine methyl esterHCID 11043221—

Reaction Conditions

Temperature20 °C

Reaction Steps

A solution of 2(S)-benzyloxycarbonylamino-3-aminopropionoic acid (2.4 g) in methanol at 0° C. was saturated with HCl gas. After stirring for 2 h at 20° C. the solution was evaporated to obtain the title compound. 1H NMR (300 MHz, CD3OD) δ7.35 (5H, m), 5.13 (2H, s), 4.50 (1H, m), 3.77 (3H, s), 3.45 (1H, m), 3.22 (1H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05872135
Source datasetuspto-grants-1999_02
ORD IDord-7661bc6a0e434bc6b0b0f7725aa50b4e
Source noteuspto-grants-1999_02