Sodium Carbonate → HCID 54067653, compound

Participants

Reaction Steps

A mixture of 6-fluoro-7-nitro-1-(phenylmethyl)-1H-4,2,1-benzoxathiazine 2,2-dioxide (1.96 g, 5.79 mmol) and SnCl2.2H2O (6.55 g, 29 mmol) in ethyl acetate (40 mL) was heated at reflux for 3 h. After the reaction was complete, ethyl acetate (400 mL) and then Na2CO3 (18.5 g) were added, and the mixture was stirred for 12 h. The resulting mixture was filtered and the filtrate was concentrated under reduced pressure to give 1.20 g of the title compound of Step G.

Provenance & Evidence