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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 363318Generated: October 30, 2026

5-Nitroindole → 3-(1,2,3,4,5,8-Hexahydroindolizin-7-yl)-5-nitro-1H-indole

https://huagongshe.com/reaction/363318

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-NitroindoleHCID 22523—
ReactantOctahydroindolizin-7-oneHCID 11240524—
Product3-(1,2,3,4,5,8-Hexahydroindolizin-7-yl)-5-nitro-1H-indoleHCID 15389760—

Reaction Steps

The 5-nitro-1H-indole (4.48 g, 27.6 mmol) and 7-octahydroindolizinone (5.0 g, 35.9 mmol) were converted to product by the procedure of Preparation IV to yield 2.99 g. (38.5%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05874427
Source datasetuspto-grants-1999_02
ORD IDord-dc789c06cbeb4af192eb5bdbdb983a48
Source noteuspto-grants-1999_02