Water → HCID 178458309, compound

Participants

Reaction Steps

A solution of 2-propoxybenzamidine methanesulfonate (2.9 g), 10% sodium hydroxide (4 ml) and ethyl 4-oxalacetate (1.6 g ) in water (8 ml) was stirred at ambient temperature for 42 hours. The reaction mixture was evaporated to dryness to yield a crude product which was washed with dilute hydrochloric acid and water to yield the title compound, 0.82 g, m.p. 179.5°-181.5° C. A sample (0.4 g) was recrystallized from ethanol to yield the pure title compound, 0.24 g, m.p. 184°-5° C.

Provenance & Evidence