HCID 67560374, compound → HCID 10572110, compound

Participants

Reaction Steps

A solution of 3.5 (0.154 g, 0.4 mmol) in EtOAc (20 mL) was treated with 10% Pd-C (0.4 g) and hydrogenated under a hydrogen balloon for 2 h. The reaction mixture was filtered and the filtrate was concentrated. The residue was purified by flash column chromatography over silica gel with EtOAc:hexanes (2:1) as eluant to give 3.3 (0.151 g, 98%) as a white solid; mp 59° C.; [α]22D +7.90° (c 1.0, CHCl3). The IR, 1H NMR, and 13C NMR were identical to those reported for the racemate 3.2. Anal. Calcd for C22H40O5 : C, 68.71; H, 10.48. Found: C, 68.81; H, 10.45.

Provenance & Evidence