HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Aminomethyl)phosphonic acid → Glyphosate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Aminomethyl)phosphonic acid | HCID 14017 | — |
| Reactant | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Glyphosate | HCID 3496 | — |
| Product | (Aminomethyl)phosphonic acid | HCID 14017 | — |
Reaction Steps
Aminomethylphosphonic acid was reductively alkylated with glyoxylic acid hydrate under catalytic hydrogenation conditions in the manner described in Example 2, except that the catalyst used was palladium metal (0.05 g), and the pH of the initial reaction mixture was 4.5. A 27% conversion of aminomethylphosphonic acid was obtained with a 93.7% selectivity to glyphosate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05874612 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-6b0ffd800a764d7a9a88d4527dff1c5a |
| Source note | uspto-grants-1999_02 |