1-(Triphenylphosphoranylidene)acetone → HCID 54517061, compound

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A solution of ethyl 4-(2-formyl-3,4,5,6-tetramethylphenyl)butyrate (5 g) and 1-triphenylphosphoranylidene-2-propanone (6 g) in toluene (100 ml) was boiled under reflux for 24 hours. The toluene was removed by evaporation under reduced pressure and the residue was purified by column chromatography on silica gel (eluant chloroform) to give ethyl 4-[2-(3-oxo-1-butenyl)-3,4,5,6-tetramethylphenyl]butyrate (5 g) as a pale brown oil. Proton nuclear magnetic resonance spectrum (CDCl3 ; δ in ppm): 1.24 (3H,t); 1.6-2.0 (2H,m); 2.1-2.4 (14H,m); 2.40 (3H,s); 2.5-2.8 (2H,m); 4.11 (2H,q); 6.12 (1H,d); 7.71 (1H,d).

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