HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Methyl 2-chloro-2-methyl-3-phenylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Methyl Methacrylate | HCID 6658 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Methyl 2-chloro-2-methyl-3-phenylpropanoate | HCID 563108 | 80% |
Reaction Steps
Following the general procedure of Example I, 280 mmols of distilled methyl methacrylate were reacted with 25 mmols of distilled aniline in 30 mL of acetonitrile and in the presence of 38 mmols of concentrated HCl and 2.5 mmols of cuprous oxide. The process resulted in an 80% yield of methyl 2-chloro-2-methyl-3-phenylpropionate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04604243 |
| Source dataset | uspto-grants-1986_08 |
| ORD ID | ord-b60d67a74f14452080482e4f43d59da6 |
| Source note | uspto-grants-1986_08 |