Ammonium Chloride → HCID 18603973, compound

Participants

Reaction Steps

The ester product from part (d) is taken into 100 ml. of 95% ethanol with stirring. Ammonium chloride (1.45 ml.) and 180 mg. of 10% palladium on carbon catalyst are added. The mixture is stirred overnight under hydrogen, filtered, and concentrated to dryness. The crude product is lyophilized and purified chromatographically to give (±)-1-[[[7-amino-3-(benzoylamino)-2-hydroxyheptyl]methylamino]carbonyl]-L-proline.

Provenance & Evidence