反应详情

Here, 3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-1-chloropropane (9 g, 0.0336 mol) is heated to 130° C. for 30 minutes with N-(2-phenylaminoethyl)-methylamine (11 g, 0.073 mol). After cooling, the reaction mixture is distributed between water and diethylether. The organic phase is separated, dried over sodium sulfate and concentrated by evaporation. The residue is recrystallized from toluene/petroleum ether.

1. temperatureAfter cooling
2. customThe organic phase is separated
3. dry with materialdried over sodium sulfate
4. concentrationconcentrated by evaporation
5. customThe residue is recrystallized from toluene/petroleum ether