3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl chloride → N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl]-2-(4-amino-3,5-dichlorophenylamino)-ethylamine

HRID 364111Notes

Reaction equation

HRID 364111 reaction equation
[CH3:1][O:2][C:3]1[C:19]([O:20][CH3:21])=[CH:18][C:6]2[C:7](=[O:17])[C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14]Cl)[CH2:10][CH2:11][C:5]=2[CH:4]=1.[NH2:22][C:23]1[C:28]([Cl:29])=[CH:27][C:26]([NH:30][CH2:31][CH2:32][NH2:33])=[CH:25][C:24]=1[Cl:34]>>[CH3:1][O:2][C:3]1[C:19]([O:20][CH3:21])=[CH:18][C:6]2[C:7](=[O:17])[C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14][NH:33][CH2:32][CH2:31][NH:30][C:26]3[CH:25]=[C:24]([Cl:34])[C:23]([NH2:22])=[C:28]([Cl:29])[CH:27]=3)[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 198474313-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl chlorideHCID 202401212-(4-Amino-3,5-dichlorophenylamino)-ethylamine

Product 1

HCID 20240167N-[3-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl]-2-(4-amino-3,5-dichlorophenylamino)-ethylamine

Procedure

The title compound is prepared from 3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-1,2-dion-3-yl)-propyl chloride and 2-(4-amino-3,5-dichlorophenylamino)-ethylamine analogously to Example 6.

Sources & evidence

ORD record
ord-6eafa30697944eb799cd86980166ea4f
Source dataset
uspto-grants-1986_08
Patent number
US04604389

Reaction notes

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