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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 36412Generated: October 25, 2026

Formic Acid → 3-(3,4-Dimethoxyphenyl)propionic acid

https://huagongshe.com/reaction/36412

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormic AcidHCID 284—
ReactantVeratraldehydeHCID 8419—
Reactant2-Phenyl-1,3-dioxane-4,6-dioneHCID 933829—
SolventTriethylamineHCID 8471—
Product3-(3,4-Dimethoxyphenyl)propionic acidHCID 75019—

Reaction Steps

25 ml of the mixture of formic acid and triethylamine prepared as described in Example 1 were added to a mixture of 4.8 g (0.025 mol) of 2-phenyl-1,3-dioxane-4,6-dione (m.p.: 148° C.) and 4.15 g (0.025 mol) of veratraldehyde. The reaction was carried out according to Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05414108
Source datasetuspto-grants-1995_05
ORD IDord-c417891da0c84778979b5f07d0034772
Source noteuspto-grants-1995_05