Dicyclohexylamine → 5-[[(1-Heptenyl)carbonyl]methoxyamino]pentanoic acid

HRID 364148Notes

Reaction equation

HRID 364148 reaction equation
[CH:1]([C:11]([OH:13])=O)=[CH:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]CC.C([O:16]C(=O)CCCCI)C.C([O:26][C:27](=[O:32])[CH2:28][CH2:29][CH2:30]I)C.C1([NH:39][CH:40]2CCCCC2)CCCCC1>>[CH:2]([C:1]([CH2:11][O:13][NH:39][CH2:40][CH2:30][CH2:29][CH2:28][C:27]([OH:26])=[O:32])=[O:16])=[CH:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 4

HCID 7582DicyclohexylamineHCID 519180Hendecenoic acidHCID 4169827Ethyl 5-iodopentanoateHCID 10890062Ethyl 4-iodobutanoate

Product 1

HCID 570875895-[[(1-Heptenyl)carbonyl]methoxyamino]pentanoic acid

Procedure

Following the procedure of Example 12 except substituting 1-heptenylcarboxylic acid for 1-decenylcarboxylic acid, and ethyl-5 iodovalerate for ethyl-4-iodobutyrate and eliminating the addition of dicyclohexylamine, the title compound is obtained.

Sources & evidence

ORD record
ord-18c2b29463334349b139fd32c16c0d43
Source dataset
uspto-grants-1986_08
Patent number
US04604407

Reaction notes

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