Water → HCID 13689046, compound

HRID 364188Notes

Reaction equation

HRID 364188 reaction equation
[N+:1]([C:4]1[CH:12]=[CH:11][C:10]2[N:9]([CH2:13][CH2:14][NH:15][CH2:16][CH2:17][OH:18])[N:8]=[C:7]3[C:19]4[CH:25]=[CH:24][CH:23]=[CH:22][C:20]=4[S:21][C:5]=1[C:6]=23)([O-:3])=[O:2].[C:26]([O-:29])(=O)[CH3:27].[Na+].O.[CH3:32][C:33](OC(C)=O)=[O:34]>>[C:33]([O:18][CH2:17][CH2:16][N:15]([CH2:14][CH2:13][N:9]1[C:10]2[CH:11]=[CH:12][C:4]([N+:1]([O-:3])=[O:2])=[C:5]3[S:21][C:20]4[CH:22]=[CH:23][CH:24]=[CH:25][C:19]=4[C:7]([C:6]=23)=[N:8]1)[C:26](=[O:29])[CH3:27])(=[O:34])[CH3:32]

Participants

5

Reactant 4

HCID 962WaterHCID 7918Acetic AnhydrideHCID 517045Sodium AcetateHCID 13689030HCID 13689030, compound

Product 1

HCID 13689046HCID 13689046, compound

Conditions

Temperature
25 °C

Procedure

A mixture of 1.0 g (0.0025 mol) of 2-[[2-(5-nitro-2H[1]benzothiopyrano[4,3,2-cd]indazol-2-yl)-ethyl]amino]ethanol and 0.5 g (0.0053 mol) of sodium acetate in 50 ml of Ac2O was stirred at 25° C. for 24 hours and poured into 500 ml of H2O. The precipitate that accumulated was collected and dried to give 1.0 g of product, mp 113°-116° C.

Workup

  1. customThe precipitate that accumulated was collected
  2. customdried

Sources & evidence

ORD record
ord-47e74c7b97ff4774b05415a0188e71cb
Source dataset
uspto-grants-1986_08
Patent number
US04604390

Reaction notes

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