3-(2-Chloroethyl)-1,3-oxazolidin-2-one → HCID 13689060, compound

HRID 364194Notes

Reaction equation

HRID 364194 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]2[N:7]([CH2:11][CH2:12][N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])[N:6]=[C:5]3[C:18]4[C:24]([O:25][CH3:26])=[CH:23][CH:22]=[C:21]([O:27][CH3:28])[C:19]=4[S:20][C:3]=1[C:4]=23.Cl[CH2:30][CH2:31][N:32]1[CH2:36][CH2:35][O:34][C:33]1=[O:37]>>[CH2:14]([N:13]([CH2:16][CH3:17])[CH2:12][CH2:11][N:7]1[C:8]2[CH:9]=[CH:10][C:2]([NH:1][CH2:30][CH2:31][N:32]3[CH2:36][CH2:35][O:34][C:33]3=[O:37])=[C:3]3[S:20][C:19]4[C:21]([O:27][CH3:28])=[CH:22][CH:23]=[C:24]([O:25][CH3:26])[C:18]=4[C:5]([C:4]=23)=[N:6]1)[CH3:15]

Participants

3

Reactant 2

HCID 756333-(2-Chloroethyl)-1,3-oxazolidin-2-oneHCID 13689059HCID 13689059, compound

Product 1

HCID 13689060HCID 13689060, compoundYield 56.9%

Procedure

A mixture of 2.2 g (0.0055 mol) of 5-amino-N,N-diethyl-7,10-dimethoxy-2H[1]benzothiopyrano[4,3,2-cd]indazole-2-ethanamine and 1.6 g (0.011 mole) of 3-(β-chloroethyl)-2-oxazolidinone was treated in the manner described in Example 42 to furnish 1.6 g of the title compound, mp greater than 250° C. dec.

Workup

  1. additionwas treated in the manner

Sources & evidence

ORD record
ord-b7b959f1817c4092a6b14d691c9467ec
Source dataset
uspto-grants-1986_08
Patent number
US04604390

Reaction notes

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