2-Bromoethylamine hydrobromide → HCID 131714812, compound

HRID 364199Notes

Reaction equation

HRID 364199 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]2[N:7]([CH2:11][CH2:12][N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])[N:6]=[C:5]3[C:18]4[CH:24]=[CH:23][CH:22]=[C:21]([O:25][CH3:26])[C:19]=4[S:20][C:3]=1[C:4]=23.Br.[Br:28][CH2:29][CH2:30][NH2:31]>CCO>[BrH:28].[CH2:16]([N:13]([CH2:14][CH3:15])[CH2:12][CH2:11][N:7]1[C:8]2[CH:9]=[CH:10][C:2]([NH:1][CH2:29][CH2:30][NH2:31])=[C:3]3[S:20][C:19]4[C:21]([O:25][CH3:26])=[CH:22][CH:23]=[CH:24][C:18]=4[C:5]([C:4]=23)=[N:6]1)[CH3:17]

Participants

4

Reactant 2

HCID 27742172-Bromoethylamine hydrobromideHCID 20240197HCID 20240197, compound

Product 1

HCID 131714812HCID 131714812, compoundYield 34.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of a solution of 3.5 g (0.0095 mol) of 5-amino-N,N-diethyl-7-methoxy-2H[1]benzothiopyrano-[4,3,2-cd]indazole-2-ethanamine and 5.8 g (0.0283 mol) of 2-bromoethylamine, hyrobromide, in 30 ml of EtOH as described in Example 38 gave 1.6 g of product.

Sources & evidence

ORD record
ord-01c4d1f8cd4c499a8693087d10971a3a
Source dataset
uspto-grants-1986_08
Patent number
US04604390

Reaction notes

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