HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 36420Generated: October 25, 2026
Formic Acid → 3-(4-Nitrophenyl)propanoic acid
https://huagongshe.com/reaction/36420
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | 4-Nitrobenzaldehyde | HCID 541 | — |
| Reactant | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 3-(4-Nitrophenyl)propanoic acid | HCID 85526 | — |
Reaction Steps
3.60 g (0.025 mol) of Meldrum's acid and 3.8 g (0.025 mol) of p-nitrobenzaldehyde were weighed in to 25 ml of the mixture of formic acid and triethylamine prepared as described in Example l. The reaction mixture was heated to 105° C. during 1 hour and reacted at the same temperature for 1 hour. The product was isolated according to Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05414108 |
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| Source dataset | uspto-grants-1995_05 |
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| ORD ID | ord-34d196c1fab248819f8d6892c2587e9f |
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| Source note | uspto-grants-1995_05 |
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