Acetic Anhydride → HCID 13339914, compound

HRID 364228Notes

Reaction equation

HRID 364228 reaction equation
[NH2:1][CH2:2][C:3]1[N:8]=[C:7]([S:9][CH3:10])[N:6]=[C:5]([S:11][CH3:12])[CH:4]=1.[C:13](OC(=O)C)(=[O:15])[CH3:14]>>[C:13]([NH:1][CH2:2][C:3]1[N:8]=[C:7]([S:9][CH3:10])[N:6]=[C:5]([S:11][CH3:12])[CH:4]=1)(=[O:15])[CH3:14]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 13339913HCID 13339913, compound

Product 1

HCID 13339914HCID 13339914, compound

Procedure

A mixture of 11 g (16.5 mmole) of 6-aminomethyl-2,4-bis(methylthio)pyrimidine and 75 ml of acetic anhydride was stirred at room temperature for 16 hours, then evaporated. The residue was isolated by filtration and washed with a small amount of methanol to provide white solid 6-acetylaminomethyl-2,4-bis(methylthio)pyrimidine. The structural assignment was supported by infrared spectral analysis.

Workup

  1. customevaporated
  2. customThe residue was isolated by filtration
  3. washwashed with a small amount of methanol

Sources & evidence

ORD record
ord-ceaa64cf5e934edf9de293bb9ae35b06
Source dataset
uspto-grants-1986_08
Patent number
US04604466

Reaction notes

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