Acetic Anhydride → HCID 21793933, compound

HRID 364233Notes

Reaction equation

HRID 364233 reaction equation
[NH2:1][CH2:2][C:3]1[N:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([O:11][CH3:12])[CH:4]=1.[C:13](OC(=O)C)(=[O:15])[CH3:14]>S(=O)(=O)(O)O>[C:13]([NH:1][CH2:2][C:3]1[N:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([O:11][CH3:12])[CH:4]=1)(=[O:15])[CH3:14]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 21793930HCID 21793930, compound

Product 1

HCID 21793933HCID 21793933, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidCatalyst

Procedure

A sample of 6-aminomethyl-2,4-dimethoxypyrimidine (from Example 11) was stirred at 20° C. with excess acetic anhydride and a few drops of sulfuric acid for about 20 hours. Evaporation, extraction into chloroform and reisolation provided 6-acetylaminomethyl-2,4-dimethoxypyrimidine.

Workup

  1. customEvaporation, extraction into chloroform and reisolation

Sources & evidence

ORD record
ord-6ecacb7b703f4787acdda922e44a8f6b
Source dataset
uspto-grants-1986_08
Patent number
US04604466

Reaction notes

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